SCHEMBL2580673

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2580934	0.98	CYP1A2 (0.46)	CYP1A2KMT2ATDP1CYP3A4TSHR
	SCHEMBL16480294	0.86	DGKA (0.45)	CYP1A2KMT2ATDP1CYP3A4TSHR
	SCHEMBL8095315	0.85	DGKA (0.51)	KMT2ATDP1CYP3A4TSHRALDH1A1
	SCHEMBL9315300	0.83	DGKA (0.57)	KMT2ATSHRALDH1A1DGKAMAPT
	SCHEMBL16312502	0.83	DGKA (0.43)	TDP1CYP3A4TSHRALDH1A1ATM
	SCHEMBL7778506	0.82	TSHR (0.50)	KMT2ATSHRALDH1A1HSD17B10L3MBTL1
	SCHEMBL16374096	0.82	DGKA (0.43)	TDP1CYP3A4TSHRALDH1A1ATM
	SCHEMBL5855176	0.81	CYP1A2 (0.46)	CYP1A2KMT2ATDP1CYP3A4TSHR
	SCHEMBL8102988	0.81	DNM1 (0.58)	CYP1A2TDP1CYP3A4TSHRALDH1A1
	SCHEMBL7789654	0.81	CYP1A2 (0.42)	CYP1A2KMT2ATDP1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.