Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MC4R | P32245 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10596238 | 0.86 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNAMC4RBCHECHRNA7 | |
| SCHEMBL5809206 | 0.77 | FAAH (0.73) | SMN1; SMN2LMNAMC4RBCHECHRNA7 | |
| SCHEMBL1472615 | 0.76 | EPHX1 (0.35) | SMN1; SMN2RAB9ANPC1GAAEPHX1 | |
| SCHEMBL13531412 | 0.75 | SLC18A3 (0.39) | POLB | |
| SCHEMBL2576912 | 0.75 | FAAH (0.76) | SMN1; SMN2LMNAMC4RBCHECHRNA7 | |
| SCHEMBL1472617 | 0.74 | SERPINE1 (0.33) | EPHX1 | |
| SCHEMBL27544341 | 0.73 | BCHE (0.66) | SMN1; SMN2LMNAMC4RBCHECHRNA7 | |
| SCHEMBL8737173 | 0.72 | HPGD (0.50) | SMN1; SMN2LMNAMC4RRAB9AFAAH | |
| SCHEMBL4630613 | 0.72 | EPHX1 (0.33) | SMN1; SMN2RAB9ANPC1MAPTEPHX1 | |
| Acetic Acid SCHEMBL15140949 | 0.72 | SLC18A3 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593077-B1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE AG (DE) | 2016-11-02 | — | — | EP | disclosed |
| EP-2593077-B1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE AG (DE) | 2016-11-02 | — | — | EP | disclosed |
| CN-103025310-B | Cyclohexyl carbamate compounds as skin and/or hair lightening actives | SYMRISE AG (DE) | 2016-01-27 | — | — | CN | disclosed |
| US-9072676-B2 | Cyclohexyl carbamate compounds as skin and/or hair lightening actives | SYMRISE AG (DE) | 2015-07-07 | — | — | US | disclosed |
| US-9072676-B2 | Cyclohexyl carbamate compounds as skin and/or hair lightening actives | SYMRISE AG (DE) | 2015-07-07 | — | — | US | disclosed |
| US-9072676-B2 | Cyclohexyl carbamate compounds as skin and/or hair lightening actives | SYMRISE AG (DE) | 2015-07-07 | — | — | US | disclosed |
| US-20130156710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE AG (DE) | 2013-06-20 | — | — | US | disclosed |
| US-20130156710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE AG (DE) | 2013-06-20 | — | — | US | disclosed |
| US-20130156710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE AG (DE) | 2013-06-20 | — | — | US | disclosed |
| EP-2593077-A2 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | Symrise AG (DE) | 2013-05-22 | — | — | EP | disclosed |
| EP-2389922-A1 | Cyclohexyl carbamate compounds as anti-ageing actives | Symrise AG (DE) | 2011-11-30 | — | — | EP | disclosed |
| EP-2389922-A1 | Cyclohexyl carbamate compounds as anti-ageing actives | Symrise AG (DE) | 2011-11-30 | — | — | EP | disclosed |
| WO-2010122178-A2 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE GMBH & CO. KG (DE) | 2010-10-28 | — | — | WO | disclosed |
| WO-2010122178-A2 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE GMBH & CO. KG (DE) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130156710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | CBR1, CYP2A13, CBR3 | SMN1; SMN2 4820/4885LMNA 1211/4885MC4R 1392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.