SCHEMBL10596238

SCHEMBL10596238

O=C(Nc1ccccc1)OC1CCCCC1OC(=O)Nc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.69
LMNA P02545 1/20 0.69
MC4R P32245 1/20 0.69
BCHE P06276 5/20 0.63
CHRNA7 P36544 2/20 0.63
ACHE P22303 2/20 0.63
RAB9A P51151 2/20 0.62
NPC1 O15118 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
FAAH O00519 1/20 0.56
MGLL Q99685 1/20 0.56
HPGD P15428 1/20 0.54
POLB P06746 1/20 0.53
EPHX2 P34913 2/20 0.51
EPHX1 P07099 1/20 0.51
MAOB P27338 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2580690 0.86 SMN1; SMN2 (0.57) SMN1; SMN2LMNAMC4RBCHECHRNA7
SCHEMBL5809206 0.86 FAAH (0.73) SMN1; SMN2LMNAMC4RBCHECHRNA7
SCHEMBL2576912 0.84 FAAH (0.76) SMN1; SMN2LMNAMC4RBCHECHRNA7
SCHEMBL27544341 0.81 BCHE (0.66) SMN1; SMN2LMNAMC4RBCHECHRNA7
SCHEMBL1027579 0.80 LMNA (0.53) SMN1; SMN2LMNAMC4RBCHECHRNA7
SCHEMBL372135 0.78 CHRNA7 (1.00) BCHECHRNA7ACHERAB9ANPC1
SCHEMBL373197 0.78 CHRNA7 (1.00) BCHECHRNA7ACHERAB9ANPC1
SCHEMBL372949 0.78 CHRNA7 (1.00) BCHECHRNA7ACHERAB9ANPC1
SCHEMBL7266561 0.77 LMNA (0.54) SMN1; SMN2LMNAMC4RBCHECHRNA7
SCHEMBL372913 0.77 CHRNA7 (0.86) SMN1; SMN2LMNAMC4RBCHECHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4888321-A SUBBING AND RECORDING LAYERS EACH CONTAINING HEAT FUSIBLE MATERIAL WITH DEFINED MELTING POINT FUJI PHOTO FILM CO., LTD. (JP) 1989-12-19 US disclosed
US-4520377-A COLOR FORMING LAYER COMO/SED OF ELECTRON DONATING COLORLESS DYE, ELECTRON ACCEPTING COMPOUND, NAPHTHOL UREA AND/OR URETHANE DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1985-05-28 US disclosed
US-4401717-A CONTAINING A CHROMOGEN, A PHENOL LAND A UREA OR CARBAMATE; THERMOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1983-08-30 US disclosed