Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.35 |
| ▸ | RAB9A | P51151 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CASP3 | P42574 | 2/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21314229 | 0.88 | HTT (0.39) | NPC1RAB9AMAPTHTTLMNA | |
| SCHEMBL2589600 | 0.86 | NPC1 (0.43) | NPC1RAB9AMAPTHTTLMNA | |
| SCHEMBL2587974 | 0.85 | NPC1 (0.40) | NPC1RAB9AMAPTAMY1AHTT | |
| SCHEMBL9100960 | 0.84 | CACNA1D (0.39) | NPC1RAB9AL3MBTL1KDM4EPOLB | |
| SCHEMBL1100175 | 0.82 | KDM4E (0.35) | NPC1RAB9AMAPTAMY1AHTT | |
| SCHEMBL825195 | 0.76 | MAPT (0.32) | NPC1RAB9AMAPTLMNACASP3 | |
| SCHEMBL29823665 | 0.76 | MAPT (0.32) | NPC1RAB9AMAPTLMNACASP3 | |
| SCHEMBL20943569 | 0.76 | POLB (0.35) | NPC1RAB9AMAPTHTTLMNA | |
| SCHEMBL20943568 | 0.74 | MAPT (0.32) | NPC1RAB9AMAPTHTTLMNA | |
| SCHEMBL13412683 | 0.72 | NPC1 (0.46) | NPC1RAB9AMAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303415-B1 | VISIBLE-LIGHT PHOTOINITIATORS AND USES THEREOF | ALCON INC (CH) | 2022-12-28 | — | — | EP | claimed |
| EP-3743270-B1 | CAST-MOLDING PROCESS FOR PRODUCING UV-ABSORBING CONTACT LENSES | ALCON INC (CH) | 2022-06-08 | — | — | EP | claimed |
| EP-3052534-B1 | METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES | NOVARTIS AG (CH) | 2019-05-01 | — | — | EP | claimed |
| EP-2564245-A1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | Novartis AG (CH) | 2013-03-06 | — | — | EP | claimed |
| WO-2011137142-A1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | NOVARTIS AG (CH) | 2011-11-03 | — | — | WO | claimed |
| EP-3634732-B1 | METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES | ALCON RES LTD (US) | 2021-07-21 | — | — | EP | disclosed |
| EP-2564245-A1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | Novartis AG (CH) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011137142-A1 | INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES | NOVARTIS AG (CH) | 2011-11-03 | — | — | WO | disclosed |