SCHEMBL825195

SCHEMBL825195

C=C(C)C(=O)OCc1cc(OC)cc(-n2nc3ccc(F)cc3n2)c1O

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.32
NPC1 O15118 7/20 0.32
RAB9A P51151 7/20 0.32
KDM4E B2RXH2 4/20 0.32
ALDH1A1 P00352 3/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
KMT2A Q03164 2/20 0.32
LMNA P02545 1/20 0.32
CASP3 P42574 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
GAA P10253 1/20 0.32
MEN1 O00255 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TP53 P04637 3/20 0.32
RXFP1 Q9HBX9 1/20 0.32
HPGD P15428 3/20 0.31
HSD17B10 Q99714 2/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29823665 1.00 MAPT (0.32) MAPTNPC1RAB9AKDM4EALDH1A1
SCHEMBL1101121 0.91 ALDH1A1 (0.36) MAPTNPC1RAB9AKDM4EALDH1A1
SCHEMBL1100680 0.89 NPC1 (0.37) MAPTNPC1RAB9AKDM4EALDH1A1
SCHEMBL1100484 0.89 NPC1 (0.38) MAPTNPC1RAB9AKDM4EALDH1A1
SCHEMBL1100373 0.88 MAPT (0.34) MAPTNPC1RAB9AKDM4EALDH1A1
SCHEMBL1098652 0.88 NPC1 (0.38) MAPTNPC1RAB9AKDM4EALDH1A1
SCHEMBL29153159 0.88 TDP1 (0.33) KDM4EALDH1A1L3MBTL1
SCHEMBL29565119 0.88 CSNK1D (0.36) MAPTNPC1RAB9AKMT2ALMNA
SCHEMBL825192 0.88 CSNK1D (0.36) MAPTNPC1RAB9AKMT2ALMNA
SCHEMBL10020867 0.87 MAPT (0.33) MAPTNPC1RAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250223392-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC (CH) 2025-07-10 US claimed
US-12286501-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2025-04-29 US claimed
US-20240254269-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC. (CH) 2024-08-01 US claimed
US-11926689-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2024-03-12 US claimed
EP-3303415-B1 VISIBLE-LIGHT PHOTOINITIATORS AND USES THEREOF ALCON INC (CH) 2022-12-28 EP claimed
US-20220380509-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC. (CH) 2022-12-01 US claimed
US-11453736-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2022-09-27 US claimed
EP-3743270-B1 CAST-MOLDING PROCESS FOR PRODUCING UV-ABSORBING CONTACT LENSES ALCON INC (CH) 2022-06-08 EP claimed
US-11111327-B2 Cast-molding process for producing UV-absorbing contact lenses ALCON INC. (CH) 2021-09-07 US claimed
US-20210009743-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC. (CH) 2021-01-14 US claimed
EP-3052534-A1 METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES Novartis AG (CH) 2016-08-10 EP claimed
US-20150094393-A1 METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES ALCON INC. (CH) 2015-04-02 US claimed
WO-2015048035-A1 METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES NOVARTIS AG (CH) 2015-04-02 WO claimed
EP-2346840-B1 UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS NOVARTIS AG (CH) 2013-12-25 EP claimed
US-8262948-B2 Intraocular lenses with combinations of UV absorbers and blue light chromophores NOVARTIS AG (CH) 2012-09-11 US claimed
US-8153703-B2 UV/visible light absorbers for ophthalmic lens materials NOVARTIS AG (CH) 2012-04-10 US claimed
US-20110266505-A1 INTRAOCULAR LENSES WITH COMBINATIONS OF UV ABSORBERS AND BLUE LIGHT CHROMOPHORES ALCON INC. (CH) 2011-11-03 US claimed
EP-2346840-A1 UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS Alcon, Inc. (CH) 2011-07-27 EP claimed
WO-2010053917-A1 UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS ALCON, INC. (CH) 2010-05-14 WO claimed
US-20100113641-A1 UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS ALCON, INC. (CH) 2010-05-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113641-A1 UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS UACA, CRYZ, CRYAA MAPT 45/4885NPC1 3813/4885RAB9A 4701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.