Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 9/20 | 0.71 |
| ▸ | HTR2C | P28335 | 5/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | MPO | P05164 | 3/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25809492 | 0.88 | HTR2A (0.56) | HTR2AHTR2CMPOHRH1OPRM1 | |
| SCHEMBL25809589 | 0.84 | HTR2A (0.54) | HTR2AHTR2CTAAR1MPOHRH1 | |
| SCHEMBL25809486 | 0.81 | HTR2A (0.55) | HTR2AHTR2CMPOKMT2AMEN1 | |
| SCHEMBL27002040 | 0.79 | HTR2A (0.72) | HTR2AHTR2CTAAR1MPOHRH1 | |
| SCHEMBL25809490 | 0.78 | HTR2A (0.60) | HTR2AHTR2CKMT2AMEN1KDM4E | |
| SCHEMBL25809531 | 0.78 | HTR2A (0.76) | HTR2AHTR2CTAAR1MPOHRH1 | |
| SCHEMBL25809437 | 0.78 | HTR2A (0.63) | HTR2AHTR2CKMT2A | |
| SCHEMBL27002133 | 0.78 | HTR2A (0.70) | HTR2AHTR2CTAAR1MPOHRH1 | |
| SCHEMBL25809489 | 0.77 | HTR2A (0.61) | HTR2AHTR2CKDM4EALDH1A1LMNA | |
| SCHEMBL25809444 | 0.77 | HTR2A (0.55) | HTR2AHTR2CKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130181-A1 | PHENETHLYAMINES AND METHODS OF PREPARATION THEREOF | BRIGHT MINDS BIOSCIENCES INC. (CA) | 2023-07-13 | — | — | WO | disclosed |