Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 12/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25809490 | 0.89 | HTR2A (0.60) | HTR2ACACNA1GCACNA1BKDM4EALDH1A1 | |
| SCHEMBL25809444 | 0.87 | HTR2A (0.55) | HTR2ASLC6A4PTGES2SMN1; SMN2KDM4E | |
| SCHEMBL25809437 | 0.81 | HTR2A (0.63) | HTR2ABCHEHTR2C | |
| SCHEMBL25809486 | 0.80 | HTR2A (0.55) | HTR2ASMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL25809485 | 0.77 | HTR2A (0.71) | HTR2ASMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL25809492 | 0.77 | HTR2A (0.56) | HTR2AHTR2C | |
| SCHEMBL25809589 | 0.75 | HTR2A (0.54) | HTR2AKDM4EALDH1A1BCHEHTR2C | |
| SCHEMBL25809647 | 0.75 | HTR2A (0.51) | HTR2ASLC6A4PTGES2HTR2C | |
| SCHEMBL24734851 | 0.72 | HTR2A (0.54) | HTR2ACACNA1GCACNA1BBCHEHTR2C | |
| SCHEMBL31218198 | 0.72 | HTR2A (0.54) | HTR2ACACNA1GCACNA1BBCHEHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130181-A1 | PHENETHLYAMINES AND METHODS OF PREPARATION THEREOF | BRIGHT MINDS BIOSCIENCES INC. (CA) | 2023-07-13 | — | — | WO | disclosed |