Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25809437 | 0.87 | HTR2A (0.63) | HTR2ACHEK1KMT2AHTR2CBCHE | |
| SCHEMBL25809444 | 0.86 | HTR2A (0.55) | HTR2ACHEK1KMT2AHTR2CBCHE | |
| SCHEMBL25809492 | 0.84 | HTR2A (0.56) | HTR2AMPOCHEK1KMT2AHTR2C | |
| SCHEMBL25809485 | 0.81 | HTR2A (0.71) | HTR2AMPOKMT2AMEN1HTR2C | |
| SCHEMBL25809490 | 0.81 | HTR2A (0.60) | HTR2ACHEK1KMT2AMEN1HTR2C | |
| SCHEMBL25809489 | 0.80 | HTR2A (0.61) | HTR2AHTR2CBCHEKDM4ELMNA | |
| SCHEMBL25809589 | 0.75 | HTR2A (0.54) | HTR2AMPOHTR2CBCHEKDM4E | |
| SCHEMBL23235818 | 0.75 | AR (0.45) | HTR2AHTR2CLMNA | |
| SCHEMBL25809647 | 0.75 | HTR2A (0.51) | HTR2ACHEK1HTR2C | |
| SCHEMBL30068214 | 0.73 | HTR2A (0.54) | HTR2AMPOKMT2AMEN1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130181-A1 | PHENETHLYAMINES AND METHODS OF PREPARATION THEREOF | BRIGHT MINDS BIOSCIENCES INC. (CA) | 2023-07-13 | — | — | WO | disclosed |