Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.35 |
| ▸ | CHRNA6 | Q15825 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12385823 | 0.86 | ALDH1A1 (0.51) | ALDH1A1NPC1LMNAKDM4EMEN1 | |
| SCHEMBL25468390 | 0.86 | ALDH1A1 (0.51) | ALDH1A1NPC1LMNAKDM4EMEN1 | |
| SCHEMBL21430362 | 0.81 | ALDH1A1 (0.65) | ALDH1A1NPC1LMNAMEN1POLB | |
| SCHEMBL27292932 | 0.81 | KDM4E (0.37) | ALDH1A1CHRNB2CHRNA4KDM4ECHRNA3 | |
| SCHEMBL2606053 | 0.81 | ALDH1A1 (0.62) | ALDH1A1NPC1LMNAKDM4EMEN1 | |
| SCHEMBL25824934 | 0.79 | NPC1 (0.46) | ALDH1A1NPC1CHRNB2CHRNA4LMNA | |
| SCHEMBL14873798 | 0.78 | CHRNB2 (0.39) | CHRNB2CHRNA4KDM4ECHRNA3CHRNB3 | |
| SCHEMBL18685371 | 0.78 | CHRNB2 (0.39) | CHRNB2CHRNA4KDM4ECHRNA3CHRNB3 | |
| SCHEMBL24491611 | 0.78 | KDM4E (0.36) | ALDH1A1CHRNB2CHRNA4LMNAKDM4E | |
| SCHEMBL18685401 | 0.78 | CHRNB2 (0.39) | CHRNB2CHRNA4KDM4ECHRNA3CHRNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235380-A1 | MACROLIDES FOR TREATING GENETIC DISEASES | ZIKANI THERAPEUTICS, INC. (US) | 2023-12-07 | — | — | WO | disclosed |
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |