Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.39 |
| ▸ | CHRNA6 | Q15825 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16230440 | 0.87 | NPC1 (0.55) | NPC1POLBMEN1MAPTKMT2A | |
| SCHEMBL22699050 | 0.83 | KMT2A (0.48) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL26936170 | 0.83 | KMT2A (0.65) | NPC1POLBMEN1MAPTKMT2A | |
| SCHEMBL14174867 | 0.82 | NPC1 (0.69) | NPC1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL24491469 | 0.81 | CHRNB2 (0.41) | NPC1POLBMEN1MAPTKMT2A | |
| SCHEMBL24023958 | 0.79 | CHRNB2 (0.36) | NPC1CHRNB2CHRNA4CHRNA3CHRNB3 | |
| SCHEMBL24492121 | 0.79 | CHRNB2 (0.36) | NPC1MEN1KMT2ACHRNB2CHRNA4 | |
| SCHEMBL25810241 | 0.79 | ALDH1A1 (0.39) | NPC1POLBMEN1MAPTKMT2A | |
| SCHEMBL24733577 | 0.79 | NPC1 (0.35) | NPC1CHRNB2CHRNA4CHRNA3CHRNB3 | |
| SCHEMBL27274900 | 0.79 | CHRNB2 (0.38) | NPC1POLBMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |