Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30492838 | 1.00 | LGMN (0.47) | LGMNMAPTNPSR1MEN1KMT2A | |
| SCHEMBL30492806 | 0.88 | LGMN (0.45) | LGMNMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL25810757 | 0.88 | LGMN (0.45) | LGMNMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30492857 | 0.87 | LGMN (0.43) | LGMNMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL31025971 | 0.87 | LGMN (0.43) | LGMNMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL25809773 | 0.86 | HRH4 (0.43) | LGMNMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL30492874 | 0.85 | CHRNA7 (0.43) | LGMNMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL31025977 | 0.85 | LGMN (0.51) | LGMNMAPTNPSR1MEN1KMT2A | |
| SCHEMBL31026002 | 0.85 | KDM4E (0.47) | MAPTALDH1A1KDM4ESMN1; SMN2PTPN2 | |
| SCHEMBL30492856 | 0.85 | LGMN (0.51) | LGMNMAPTNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118488951-A | Fused bicyclic heteroaryl amide compounds as inhibitors of protein aggregation | 上海京新生物医药有限公司 | 2024-08-13 | — | — | CN | disclosed |
| WO-2023125376-A1 | FUSED BICYCLIC HETEROARYL AMIDE COMPOUND AS PROTEIN AGGREGATION INHIBITOR | 上海京新生物医药有限公司 | 2023-07-06 | — | — | WO | disclosed |