Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 4/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30492806 | 1.00 | LGMN (0.45) | LGMNTMEM97SIGMAR1PDE5APTPN2 | |
| SCHEMBL25810272 | 0.88 | LGMN (0.47) | LGMNPTPN2CHRNA7MAPTGAA | |
| SCHEMBL30492838 | 0.88 | LGMN (0.47) | LGMNPTPN2CHRNA7MAPTGAA | |
| SCHEMBL30492883 | 0.84 | CHRNA7 (0.42) | TMEM97SIGMAR1PLK1CHRNA7STAT3 | |
| SCHEMBL25810758 | 0.84 | CHRNA7 (0.42) | TMEM97SIGMAR1PLK1CHRNA7STAT3 | |
| SCHEMBL31025971 | 0.84 | LGMN (0.43) | LGMNPTPN2CHRNA7MAPTGAA | |
| SCHEMBL30492857 | 0.84 | LGMN (0.43) | LGMNPTPN2CHRNA7MAPTGAA | |
| SCHEMBL25809773 | 0.83 | HRH4 (0.43) | LGMNPTPN2MAPTGAAKDM4E | |
| SCHEMBL30492874 | 0.82 | CHRNA7 (0.43) | LGMNPTPN2CHRNA7MAPTGAA | |
| SCHEMBL31025977 | 0.82 | LGMN (0.51) | LGMNMAPTGAAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118488951-A | Fused bicyclic heteroaryl amide compounds as inhibitors of protein aggregation | 上海京新生物医药有限公司 | 2024-08-13 | — | — | CN | disclosed |
| WO-2023125376-A1 | FUSED BICYCLIC HETEROARYL AMIDE COMPOUND AS PROTEIN AGGREGATION INHIBITOR | 上海京新生物医药有限公司 | 2023-07-06 | — | — | WO | disclosed |