Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25810406 | 0.85 | HSD11B1 (0.44) | HSD11B1TSHRSMN1; SMN2GRM5EPHX2 | |
| SCHEMBL25824929 | 0.79 | GRM5 (0.41) | HSD11B1TSHRSMN1; SMN2GRM5EPHX2 | |
| SCHEMBL25711164 | 0.77 | HRH3 (0.40) | HSD11B1TSHRSMN1; SMN2GRM5EPHX2 | |
| SCHEMBL25810420 | 0.76 | EPHX2 (0.41) | HSD11B1GRM5EPHX2HRH3MGLL | |
| SCHEMBL25810419 | 0.76 | HSD11B1 (0.40) | HSD11B1GRM5EPHX2KMT2A | |
| SCHEMBL25810405 | 0.76 | TSHR (0.49) | TSHRSMN1; SMN2RECQLPOLBHPGD | |
| SCHEMBL25810188 | 0.75 | PIK3CD (0.43) | HSD11B1TSHRSMN1; SMN2GRM5EPHX2 | |
| SCHEMBL21324795 | 0.72 | HSD11B1 (0.53) | HSD11B1TSHRGRM5HPGDALDH1A1 | |
| SCHEMBL25810187 | 0.69 | PIK3CD (0.45) | HSD11B1TSHRSMN1; SMN2GRM5RECQL | |
| SCHEMBL25810397 | 0.69 | HSD11B1 (0.61) | HSD11B1TSHRSMN1; SMN2GRM5RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |