Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25810406 | 0.91 | HSD11B1 (0.44) | EPHX2HSD11B1HRH3GRM5 | |
| SCHEMBL25810419 | 0.85 | HSD11B1 (0.40) | EPHX2HSD11B1PIK3R1PIK3CAGRM5 | |
| SCHEMBL25810418 | 0.83 | EPHX2 (0.43) | EPHX2HRH3PIK3R1PIK3CACNR2 | |
| SCHEMBL17176111 | 0.81 | PIK3R1 (0.45) | EPHX2HSD11B1HRH3PIK3R1PIK3CA | |
| SCHEMBL17176113 | 0.81 | PIK3R1 (0.45) | EPHX2HSD11B1HRH3PIK3R1PIK3CA | |
| SCHEMBL25810199 | 0.81 | EPHX2 (0.39) | EPHX2HSD11B1HRH3GRM5CHRM4 | |
| SCHEMBL25810397 | 0.79 | HSD11B1 (0.61) | HSD11B1GRM5 | |
| SCHEMBL26159929 | 0.78 | EPHX2 (0.47) | EPHX2HRH3PIK3R1PIK3CACNR2 | |
| SCHEMBL25810409 | 0.76 | HSD11B1 (0.41) | EPHX2HSD11B1HRH3GRM5MGLL | |
| SCHEMBL25824929 | 0.75 | GRM5 (0.41) | EPHX2HSD11B1HRH3GRM5MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |