Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.61 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.41 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.41 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25810406 | 0.85 | HSD11B1 (0.44) | HSD11B1GRM5ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL25810400 | 0.83 | HSD11B1 (0.66) | HSD11B1GRM5ALDH1A1TSHRLMNA | |
| SCHEMBL18390027 | 0.81 | LMNA (0.56) | HSD11B1GRM5ALDH1A1TSHRLMNA | |
| SCHEMBL25810399 | 0.79 | ALDH1A1 (0.63) | HSD11B1GRM5ALDH1A1TSHRLMNA | |
| SCHEMBL18713235 | 0.79 | LMNA (0.58) | HSD11B1GRM5ALDH1A1TSHRLMNA | |
| SCHEMBL25810420 | 0.79 | EPHX2 (0.41) | HSD11B1GRM5 | |
| SCHEMBL22642325 | 0.79 | HSD11B1 (0.56) | HSD11B1GRM5ALDH1A1TSHRCHRNB2 | |
| SCHEMBL25810184 | 0.78 | HSD11B1 (0.51) | HSD11B1GRM5ALDH1A1TSHRLMNA | |
| SCHEMBL25840964 | 0.78 | ALDH1A1 (0.67) | HSD11B1GRM5ALDH1A1TSHRLMNA | |
| SCHEMBL18713241 | 0.77 | GRM5 (0.58) | HSD11B1GRM5ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |