Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 1/20 | 0.39 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 3/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25810387 | 0.85 | USP28 (0.41) | USP28USP25NR1H3SSTR4PTPN7 | |
| SCHEMBL25810186 | 0.82 | USP28 (0.45) | USP28USP25NR1H3SSTR4PTPN7 | |
| SCHEMBL25830115 | 0.79 | USP28 (0.38) | USP28USP25NR1H3SSTR4PTPN7 | |
| SCHEMBL25829927 | 0.79 | USP28 (0.38) | USP28USP25NR1H3SSTR4PTPN7 | |
| SCHEMBL25826057 | 0.78 | USP28 (0.37) | USP28USP25NR1H3SSTR4PTPN7 | |
| SCHEMBL25809752 | 0.78 | USP28 (0.42) | USP28USP25SSTR4PTPN7DUSP3 | |
| SCHEMBL25810527 | 0.74 | USP28 (0.39) | USP28USP25NR1H3PTPN7DUSP3 | |
| SCHEMBL25810296 | 0.73 | USP28 (0.41) | USP28USP25SSTR4P2RX3SCD | |
| SCHEMBL25825955 | 0.72 | USP28 (0.49) | USP28USP25SSTR4PTPN7DUSP3 | |
| SCHEMBL25810573 | 0.71 | USP28 (0.37) | USP28USP25SSTR4PTPN7DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |