Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 1/20 | 0.39 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 8/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.37 |
| ▸ | PTGES | O14684 | 5/20 | 0.37 |
| ▸ | PPARG | P37231 | 6/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25810386 | 0.81 | USP28 (0.41) | USP28USP25SLC6A4PSEN1ALOX5 | |
| SCHEMBL25826055 | 0.79 | USP28 (0.46) | USP28USP25SLC6A4PSEN1ALOX5 | |
| SCHEMBL18002339 | 0.78 | MRGPRX4 (0.49) | USP28USP25SLC6A4 | |
| SCHEMBL25810385 | 0.77 | USP28 (0.50) | USP28USP25SLC6A4POLBMAPT | |
| SCHEMBL23673334 | 0.76 | USP28 (0.60) | USP28USP25SLC6A4PPARGMAPT | |
| SCHEMBL30038784 | 0.76 | USP28 (0.60) | USP28USP25SLC6A4PPARGMAPT | |
| SCHEMBL25810528 | 0.74 | USP28 (0.39) | USP28USP25SLC6A4PTPN7DUSP3 | |
| SCHEMBL23673335 | 0.74 | KMT2A (0.54) | USP28USP25SLC6A4POLBMAPT | |
| SCHEMBL31215857 | 0.72 | CCR5 (0.46) | USP28USP25SLC6A4MAPT | |
| SCHEMBL25823927 | 0.72 | CCR5 (0.46) | USP28USP25SLC6A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |