Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 3/20 | 0.52 |
| ▸ | FLT4 | P35916 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 3/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.51 |
| ▸ | TEK | Q02763 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12157496 | 0.93 | MAPT (0.54) | AURKAFLT4EGFRAURKBPDGFRB | |
| SCHEMBL2588126 | 0.88 | EGFR (0.47) | AURKAFLT4EGFRAURKBPDGFRB | |
| SCHEMBL13855407 | 0.88 | KMT2A (0.49) | AURKAFLT4EGFRAURKBPDGFRB | |
| SCHEMBL2586152 | 0.88 | KMT2A (0.55) | MAPTKDM4ERAB9ANPC1NPSR1 | |
| SCHEMBL2595246 | 0.84 | MAPT (0.46) | EGFRAURKBKDRMAPTKDM4E | |
| SCHEMBL2587158 | 0.82 | MAPT (0.50) | AURKAFLT4EGFRAURKBPDGFRB | |
| SCHEMBL2578128 | 0.82 | LMNA (0.48) | MAPTKDM4ERAB9ANPC1NPSR1 | |
| SCHEMBL12157495 | 0.82 | MAPT (0.53) | AURKAFLT4EGFRAURKBPDGFRB | |
| SCHEMBL12157492 | 0.81 | KMT2A (0.54) | MAPTKDM4ERAB9ANPC1NPSR1 | |
| SCHEMBL5259792 | 0.80 | MAPT (0.58) | AURKAEGFRAURKBKDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215184-B1 | ORGANIC FLUORESCENT COMPOSITIONS | HONEYWELL INT INC (US) | 2014-08-20 | — | — | EP | disclosed |
| US-20110268896-A1 | ORGANIC FLUORESCENT COMPOSITIONS | HONEYWELL INTERNATIONAL INC. (US) | 2011-11-03 | — | — | US | disclosed |
| EP-2215184-A1 | ORGANIC FLUORESCENT COMPOSITIONS | Honeywell International Inc. (US) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009061755-A1 | ORGANIC FLUORESCENT COMPOSITIONS | HONEYWELL INTERNATIONAL INC. (US) | 2009-05-14 | — | — | WO | disclosed |
| US-20090114355-A1 | ORGANIC FLUORESCENT COMPOSITIONS | HONEYWELL INTERNATIONAL INC. (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090114355-A1 | ORGANIC FLUORESCENT COMPOSITIONS | PFAS, FUS, ACR | AURKA 501/4885FLT4 1498/4885EGFR 2450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.