Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25811597 | 0.83 | PTPN2 (0.43) | HDAC1PTPN2MAPTGAAMEN1 | |
| SCHEMBL25810716 | 0.81 | HDAC1 (0.57) | HDAC1 | |
| SCHEMBL3471180 | 0.79 | PTPN2 (0.52) | HDAC1PTPN2MAPTGAAKDM4E | |
| SCHEMBL8250276 | 0.78 | HDAC1 (0.60) | HDAC1PTPN2MAPTGAAMEN1 | |
| SCHEMBL25811696 | 0.78 | HDAC1 (0.47) | HDAC1PTPN2MAPTGAAMEN1 | |
| SCHEMBL3815251 | 0.78 | PTPN2 (0.46) | HDAC1PTPN2MAPTGAAKDM4E | |
| SCHEMBL191661 | 0.78 | PTPN2 (0.48) | HDAC1PTPN2MAPTGAAKDM4E | |
| SCHEMBL1390384 | 0.77 | HSD17B1 (0.51) | HDAC1PTPN2MAPTGAAKDM4E | |
| SCHEMBL155423 | 0.77 | PTPN2 (0.50) | HDAC1PTPN2MAPTGAAMEN1 | |
| SCHEMBL31207824 | 0.77 | HSD17B1 (0.51) | HDAC1PTPN2MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125376-A1 | FUSED BICYCLIC HETEROARYL AMIDE COMPOUND AS PROTEIN AGGREGATION INHIBITOR | 上海京新生物医药有限公司 | 2023-07-06 | — | — | WO | disclosed |