Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25810715 | 0.78 | HDAC1 (0.48) | HDAC1PTPN2MAPTGAAKMT2A | |
| SCHEMBL8250276 | 0.76 | HDAC1 (0.60) | HDAC1PTPN2MAPTGAAKMT2A | |
| SCHEMBL3504483 | 0.76 | HDAC1 (0.55) | HDAC1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL3503346 | 0.76 | HDAC1 (0.51) | HDAC1CA1CA2PTPN2MAPT | |
| SCHEMBL155423 | 0.75 | PTPN2 (0.50) | HDAC1PTPN2MAPTGAAKMT2A | |
| SCHEMBL1390384 | 0.75 | HSD17B1 (0.51) | HDAC1CA1CA2PTPN2MAPT | |
| SCHEMBL31207824 | 0.75 | HSD17B1 (0.51) | HDAC1CA1CA2PTPN2MAPT | |
| SCHEMBL1883856 | 0.75 | HDAC1 (0.54) | HDAC1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL192480 | 0.75 | HDAC1 (0.68) | HDAC1CA1CA2PTPN2MAPT | |
| SCHEMBL2238245 | 0.74 | PTPN2 (0.60) | HDAC1CA1CA2PTPN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125376-A1 | FUSED BICYCLIC HETEROARYL AMIDE COMPOUND AS PROTEIN AGGREGATION INHIBITOR | 上海京新生物医药有限公司 | 2023-07-06 | — | — | WO | disclosed |