Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.57 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25810345 | 0.87 | HDAC1 (0.63) | HDAC1BCL2L1 | |
| SCHEMBL25810715 | 0.81 | HDAC1 (0.48) | HDAC1 | |
| SCHEMBL16396231 | 0.73 | HDAC1 (0.55) | HDAC1BCL2L1TBXAS1GPR35 | |
| SCHEMBL191611 | 0.73 | TBXAS1 (0.57) | HDAC1BCL2L1TBXAS1GPR35 | |
| SCHEMBL31207829 | 0.73 | TBXAS1 (0.57) | HDAC1BCL2L1TBXAS1GPR35 | |
| SCHEMBL153935 | 0.73 | BCL2L1 (0.59) | HDAC1BCL2L1TBXAS1GPR35 | |
| SCHEMBL31435451 | 0.73 | BCL2L1 (0.59) | HDAC1BCL2L1TBXAS1GPR35 | |
| SCHEMBL15697571 | 0.71 | GPR35 (0.61) | HDAC1BCL2L1TBXAS1GPR35 | |
| SCHEMBL8250577 | 0.71 | BCL2L1 (0.61) | HDAC1BCL2L1TBXAS1GPR35 | |
| SCHEMBL26110143 | 0.71 | TBXAS1 (0.52) | HDAC1BCL2L1TBXAS1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125376-A1 | FUSED BICYCLIC HETEROARYL AMIDE COMPOUND AS PROTEIN AGGREGATION INHIBITOR | 上海京新生物医药有限公司 | 2023-07-06 | — | — | WO | disclosed |