Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 4/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | RPA1 | P27694 | 5/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30492883 | 1.00 | CHRNA7 (0.42) | CHRNA7BCL2L1PLK1NR1H4RPA1 | |
| SCHEMBL30492862 | 0.86 | USP2 (0.54) | CHRNA7BCL2L1NR1H4RPA1GPR35 | |
| SCHEMBL25810273 | 0.86 | USP2 (0.54) | CHRNA7BCL2L1NR1H4RPA1GPR35 | |
| SCHEMBL25810757 | 0.84 | LGMN (0.45) | CHRNA7PLK1TMEM97SIGMAR1STAT3 | |
| SCHEMBL30492806 | 0.84 | LGMN (0.45) | CHRNA7PLK1TMEM97SIGMAR1STAT3 | |
| SCHEMBL25296879 | 0.81 | HRH4 (0.49) | CHRNA7BCL2L1RPA1GPR35 | |
| SCHEMBL31025961 | 0.81 | HRH4 (0.49) | CHRNA7BCL2L1RPA1GPR35 | |
| SCHEMBL17858475 | 0.80 | IP6K1 (0.50) | CHRNA7BCL2L1NR1H4RPA1GPR35 | |
| SCHEMBL30492925 | 0.80 | CHRNA7 (0.46) | CHRNA7BCL2L1NR1H4RPA1GPR35 | |
| SCHEMBL25809845 | 0.80 | CHRNA7 (0.46) | CHRNA7BCL2L1NR1H4RPA1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125376-A1 | FUSED BICYCLIC HETEROARYL AMIDE COMPOUND AS PROTEIN AGGREGATION INHIBITOR | 上海京新生物医药有限公司 | 2023-07-06 | — | — | WO | disclosed |