Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25059101 | 0.86 | USP2 (0.51) | USP2SMN1; SMN2HPGDRECQLEPHX2 | |
| SCHEMBL1189317 | 0.83 | ALDH1A1 (0.56) | USP2SMN1; SMN2HPGDRECQLALDH1A1 | |
| SCHEMBL22297296 | 0.83 | USP2 (0.49) | USP2SMN1; SMN2HPGDRECQLEPHX2 | |
| SCHEMBL21686237 | 0.83 | USP2 (0.49) | USP2SMN1; SMN2HPGDRECQLEPHX2 | |
| SCHEMBL698803 | 0.82 | USP2 (0.69) | USP2SMN1; SMN2HPGDRECQLEPHX2 | |
| SCHEMBL18294 | 0.82 | USP2 (0.69) | USP2SMN1; SMN2HPGDRECQLEPHX2 | |
| SCHEMBL11339897 | 0.79 | USP2 (0.56) | USP2SMN1; SMN2HPGDRECQLEPHX2 | |
| SCHEMBL27476553 | 0.79 | USP2 (0.49) | USP2SMN1; SMN2HPGDRECQLEPHX2 | |
| SCHEMBL5572601 | 0.78 | USP2 (0.47) | USP2SMN1; SMN2HPGDRECQLEPHX2 | |
| SCHEMBL8431612 | 0.78 | SMN1; SMN2 (0.55) | USP2SMN1; SMN2HPGDRECQLEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125376-A1 | FUSED BICYCLIC HETEROARYL AMIDE COMPOUND AS PROTEIN AGGREGATION INHIBITOR | 上海京新生物医药有限公司 | 2023-07-06 | — | — | WO | disclosed |
| CN-109476664-A | New compound as autotaxin inhibitors and the pharmaceutical composition comprising it | 乐高化学生物科学股份有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-106459034-B | Carbostyril derivative as fibroblast growth factor acceptor inhibitor | 普林斯匹亚生物制药公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-106459034-A | Quinolone derivatives as fibroblast growth factor receptor inhibitors | 普林斯匹亚生物制药公司 | 2017-02-22 | — | — | CN | disclosed |