Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880962 | 0.83 | USP2 (0.50) | USP2SMN1; SMN2HPGDRECQLSTS | |
| SCHEMBL18294 | 0.78 | USP2 (0.69) | USP2SMN1; SMN2HPGDRECQLALDH1A1 | |
| SCHEMBL698803 | 0.78 | USP2 (0.69) | USP2SMN1; SMN2HPGDRECQLALDH1A1 | |
| SCHEMBL2249760 | 0.78 | USP2 (0.51) | USP2SMN1; SMN2STSMAPTTGM2 | |
| SCHEMBL25810785 | 0.78 | USP2 (0.51) | USP2SMN1; SMN2HPGDRECQLALDH1A1 | |
| SCHEMBL1514778 | 0.77 | EPHX1 (0.52) | USP2SMN1; SMN2HPGDRECQLSTS | |
| SCHEMBL1189317 | 0.75 | ALDH1A1 (0.56) | USP2SMN1; SMN2HPGDRECQLALDH1A1 | |
| SCHEMBL11339897 | 0.75 | USP2 (0.56) | USP2SMN1; SMN2HPGDRECQLALDH1A1 | |
| SCHEMBL27476553 | 0.75 | USP2 (0.49) | USP2SMN1; SMN2HPGDRECQLALDH1A1 | |
| SCHEMBL574778 | 0.75 | HPGD (0.49) | USP2SMN1; SMN2HPGDRECQLSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057815-B1 | CYCLIC AMIDE COMPOUNDS | KOWA CO (JP) | 2007-09-05 | — | — | EP | disclosed |
| CN-1114591-C | cyclic amide compound | KOWA CO (JP) | 2003-07-16 | — | — | CN | disclosed |
| CN-1291186-A | Cyclic amide compounds | KOWA CO (JP) | 2001-04-11 | — | — | CN | disclosed |