Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | BRD1 | O95696 | 1/20 | 0.32 |
| ▸ | TAF1 | P21675 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25826783 | 0.87 | MEN1 (0.38) | HTR2AMEN1KMT2AHSP90AA1ATM | |
| SCHEMBL25826787 | 0.83 | GABRA1 (0.40) | HTR2AMEN1KMT2AAKR1B1MTNR1A | |
| SCHEMBL24175936 | 0.81 | GABRA1 (0.45) | MEN1KMT2AHSP90AA1ATMGPR84 | |
| SCHEMBL25811635 | 0.81 | HTR2A (0.34) | HTR2AMEN1KMT2AAKR1B1ALDH1A1 | |
| SCHEMBL25822334 | 0.81 | HTR2A (0.34) | HTR2AMEN1KMT2AAKR1B1ALDH1A1 | |
| SCHEMBL10306619 | 0.75 | MEN1 (0.50) | MEN1KMT2AHSP90AA1ATMBRD1 | |
| SCHEMBL24652317 | 0.74 | MEN1 (0.46) | MEN1KMT2AHSP90AA1ATMBRD1 | |
| SCHEMBL9231524 | 0.73 | KMT2A (0.54) | MEN1KMT2AHSP90AA1ATMALDH1A1 | |
| SCHEMBL25962670 | 0.71 | CYP1A2 (0.42) | MEN1KMT2AHSP90AA1ATMGPR84 | |
| SCHEMBL25352843 | 0.70 | MEN1 (0.41) | MEN1KMT2AHSP90AA1ATMBRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125989-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |