Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24630603 | 0.87 | GABRA1 (0.48) | GABRA1GABRB2DAOESR1ESR2 | |
| SCHEMBL25811637 | 0.83 | HTR2A (0.37) | HTR2AAKR1B1MTNR1AMTNR1BMEN1 | |
| SCHEMBL26715054 | 0.81 | MEN1 (0.41) | GABRA1GABRB2DAOESR1ESR2 | |
| SCHEMBL25822334 | 0.79 | HTR2A (0.34) | ESR1ESR2HTR2AAKR1B1MEN1 | |
| SCHEMBL25811635 | 0.79 | HTR2A (0.34) | HTR2AAKR1B1MEN1ALDH1A1KMT2A | |
| SCHEMBL24791895 | 0.79 | ESR1 (0.47) | GABRA1GABRB2DAOESR1ESR2 | |
| SCHEMBL25962670 | 0.77 | CYP1A2 (0.42) | GABRA1GABRB2DAOESR1ESR2 | |
| SCHEMBL25955472 | 0.76 | GABRA1 (0.39) | GABRA1GABRB2DAOESR1ESR2 | |
| SCHEMBL26712981 | 0.75 | GABRA1 (0.40) | GABRA1GABRB2DAOESR1ESR2 | |
| SCHEMBL24175936 | 0.73 | GABRA1 (0.45) | GABRA1GABRB2DAOFLT3ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125989-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |