Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25811575 | 0.87 | ALDH1A1 (0.33) | MEN1ALDH1A1DNMT1CACNA1BAPBA1 | |
| SCHEMBL25811637 | 0.81 | HTR2A (0.37) | HTR2ATAAR1MEN1ALDH1A1DNMT1 | |
| SCHEMBL25822334 | 0.81 | HTR2A (0.34) | HTR2ATAAR1MEN1ALDH1A1DNMT1 | |
| SCHEMBL24697343 | 0.80 | GABRA1 (0.44) | HTR2AALDH1A1 | |
| SCHEMBL25826787 | 0.79 | GABRA1 (0.40) | HTR2AMEN1ALDH1A1KMT2AAKR1B1 | |
| Hydrochloric Acid SCHEMBL11277043 | 0.72 | TAAR1 (0.47) | HTR2ATAAR1DRD2DRD1MEN1 | |
| Hydrochloric Acid SCHEMBL30487949 | 0.70 | IDH1 (0.44) | AKR1B1NQO2 | |
| Hydrochloric Acid SCHEMBL30487955 | 0.70 | IDH1 (0.44) | AKR1B1NQO2 | |
| SCHEMBL24757921 | 0.67 | CYP1A1 (0.39) | MEN1ALDH1A1DNMT1CACNA1BAPBA1 | |
| SCHEMBL25826783 | 0.67 | MEN1 (0.38) | HTR2AMEN1ALDH1A1DNMT1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125989-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |