Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 2/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27523308 | 0.82 | EIF4A3 (0.68) | EIF4A3NSD2MEN1KMT2AMAPT | |
| SCHEMBL30147532 | 0.78 | HRH4 (0.59) | ALOX15NSD2PTPN11HDAC3HDAC1 | |
| SCHEMBL21739280 | 0.78 | HRH4 (0.56) | NSD2HRH4SETD2 | |
| SCHEMBL21235399 | 0.77 | ALOX15 (0.49) | ALOX15EIF4A3PTPN11NPC1RAB9A | |
| SCHEMBL5356682 | 0.76 | CDK1 (0.55) | ALOX15EIF4A3NPC1RAB9APOLB | |
| SCHEMBL24740292 | 0.75 | ALOX15 (0.57) | ALOX15NSD2PTPN11NPC1POLB | |
| SCHEMBL24113538 | 0.74 | HRH4 (0.54) | ALOX15PTPN11NPC1RAB9ARXFP1 | |
| SCHEMBL30147583 | 0.73 | ALOX15 (0.68) | ALOX15NPC1RAB9ARXFP1KDM4E | |
| SCHEMBL30471285 | 0.72 | IDO1 (0.54) | ALOX15NSD2PTPN11KMT2AHRH4 | |
| SCHEMBL15146698 | 0.72 | PTPN11 (0.57) | ALOX15NSD2PTPN11HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | CTRL, CTSL, CTSV | ALOX15 1455/4885EIF4A3 582/4885NSD2 2375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.