Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PARP1 | P09874 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25811886 | 0.89 | KMT2A (0.67) | ALDH1A1KDM4EL3MBTL1KMT2APARP1 | |
| SCHEMBL25811210 | 0.87 | KMT2A (0.70) | ALDH1A1KDM4EL3MBTL1KMT2APARP1 | |
| SCHEMBL25811246 | 0.76 | KMT2A (0.82) | ALDH1A1KDM4EL3MBTL1KMT2APARP1 | |
| SCHEMBL25811263 | 0.76 | KMT2A (0.85) | ALDH1A1KDM4EL3MBTL1KMT2APARP1 | |
| SCHEMBL30312303 | 0.76 | KMT2A (0.82) | ALDH1A1KDM4EL3MBTL1KMT2APARP1 | |
| SCHEMBL25811268 | 0.76 | KMT2A (0.62) | ALDH1A1KDM4EL3MBTL1KMT2APARP1 | |
| SCHEMBL25811270 | 0.76 | POLB (0.61) | ALDH1A1KDM4EL3MBTL1KMT2APARP1 | |
| SCHEMBL25811307 | 0.76 | KMT2A (0.88) | ALDH1A1KDM4EL3MBTL1KMT2APARP1 | |
| SCHEMBL25811497 | 0.76 | KMT2A (0.73) | ALDH1A1KDM4EL3MBTL1KMT2APARP1 | |
| SCHEMBL25814483 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4EL3MBTL1KMT2APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218573-A1 | INDOLE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | GALYAN BIO INC (US) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218573-A1 | INDOLE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | HTT, HYPK, PARK7 | ALDH1A1 4430/4885KDM4E 1465/4885L3MBTL1 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.