SCHEMBL25812366

SCHEMBL25812366

CCCN1Cc2ccccc2-c2c(nnn2C)-c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
GRM1 Q13255 2/20 0.36
GRM5 P41594 1/20 0.36
SLC9A1 P19634 1/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
SIGMAR1 Q99720 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
SIRT1 Q96EB6 1/20 0.32
NPY5R Q15761 1/20 0.32
LMNA P02545 1/20 0.32
PARP1 P09874 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22180487 0.93 SLC9A1 (0.38) ALDH1A1SLC9A1CYP2D6CYP2C9CYP2C19
SCHEMBL16984337 0.91 NPY5R (0.39) ALDH1A1MEN1KMT2AGRM1GRM5
SCHEMBL22210696 0.90 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ASLC9A1CYP2D6
SCHEMBL23897715 0.85 MEN1 (0.36) ALDH1A1MEN1KMT2AGRM1GRM5
SCHEMBL26502372 0.85 PARP1 (0.32) CYP2D6CYP2C9CYP2C19KDM4EALOX15
SCHEMBL23202580 0.84 MEN1 (0.35) ALDH1A1MEN1KMT2AGRM1GRM5
SCHEMBL27269680 0.83 SLC9A1 (0.38) ALDH1A1MEN1KMT2AGRM1GRM5
SCHEMBL16984175 0.82 SLC9A1 (0.34) ALDH1A1KMT2ASLC9A1KDM4ETSHR
SCHEMBL20795892 0.81 NPY5R (0.39) ALDH1A1MEN1KMT2AGRM1GRM5
SCHEMBL21286499 0.80 SLC9A1 (0.33) SLC9A1ADRA2CKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024096577-A1 COMPOUND COMPRISING FC-BINDING UNIT, AND CONJUGATE PREPARED USING SAME 앱티스 주식회사 2024-05-10 WO disclosed
US-20230203579-A1 NANOARRAYS AND METHODS OF USE THEREOF FIRST-CITIZENS BANK & TRUST COMPANY 2023-06-29 US disclosed