Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22180487 | 0.95 | SLC9A1 (0.38) | ALDH1A1CYP2D6CYP2C19CYP1A2SLC9A1 | |
| SCHEMBL25812366 | 0.90 | ALDH1A1 (0.39) | ALDH1A1CYP2D6CYP2C19SLC9A1MEN1 | |
| SCHEMBL16984337 | 0.87 | NPY5R (0.39) | ALDH1A1CYP2D6CYP2C19SLC9A1MEN1 | |
| SCHEMBL20226549 | 0.85 | ALDH1A1 (0.36) | ALDH1A1CYP2D6CYP2C19CYP1A2SLC9A1 | |
| SCHEMBL23961907 | 0.81 | SLC9A1 (0.46) | ALDH1A1CYP2D6CYP2C19CYP1A2SLC9A1 | |
| SCHEMBL26502372 | 0.81 | PARP1 (0.32) | CYP2D6CYP2C19HTR7DRD2DRD5 | |
| SCHEMBL20998964 | 0.81 | DRD2 (0.34) | ALDH1A1CYP2D6CYP2C19CYP1A2SLC9A1 | |
| SCHEMBL26504972 | 0.80 | SLC9A1 (0.45) | ALDH1A1CYP2D6CYP2C19CYP1A2SLC9A1 | |
| SCHEMBL5449154 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CYP2D6CYP2C19CYP1A2CES1 | |
| SCHEMBL16984175 | 0.79 | SLC9A1 (0.34) | ALDH1A1SLC9A1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760775-B2 | Steroids and protein-conjugates thereof | REGENERON PHARMACEUTICALS, INC. | 2023-09-19 | — | — | US | disclosed |
| US-20210040144-A1 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. | 2021-02-11 | — | — | US | disclosed |
| US-10711032-B2 | Steroids and protein-conjugates thereof | REGENERON PHARMACEUTICALS, INC. (US) | 2020-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10711032-B2 | Steroids and protein-conjugates thereof | SERPINA6, NR3C1, NR3C2 | ALDH1A1 4143/4885CYP2D6 4440/4885CYP2C19 4573/4885 |
| US-20210040144-A1 | STEROIDS AND PROTEIN-CONJUGATES THEREOF | SERPINA6, NR3C1, NR3C2 | ALDH1A1 4113/4885CYP2D6 4445/4885CYP2C19 4575/4885 |
| US-11760775-B2 | Steroids and protein-conjugates thereof | SERPINA6, NR3C1, NR3C2 | ALDH1A1 4113/4885CYP2D6 4445/4885CYP2C19 4575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.