SCHEMBL2811454

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2811460	1.00	LMNA (0.48)	LMNAL3MBTL1MMP13ALDH1A1SMN1; SMN2
	SCHEMBL2581335	0.85	AKR1C3 (0.38)	ALDH1A1AKR1C3KMT2AMEN1MAPT
	SCHEMBL219559	0.85	AKR1C3 (0.38)	ALDH1A1AKR1C3KMT2AMEN1MAPT
	SCHEMBL2808566	0.85	CA1 (0.48)	LMNAALDH1A1KMT2AHTTNPSR1
	SCHEMBL2808572	0.85	CA1 (0.48)	LMNAALDH1A1KMT2AHTTNPSR1
	SCHEMBL821031	0.84	AKR1C3 (0.50)	L3MBTL1ALDH1A1AKR1C3KMT2AHTT
	SCHEMBL156818	0.84	AKR1C3 (0.50)	L3MBTL1ALDH1A1AKR1C3KMT2AHTT
	SCHEMBL2811418	0.83	MEN1 (0.44)	L3MBTL1ALDH1A1SMN1; SMN2AKR1C3MAOB
	SCHEMBL13846155	0.83	CAPN1 (0.38)	AKR1C3HPGDMAPT
	SCHEMBL7098474	0.83	CYP19A1 (0.39)	LMNAALDH1A1SMN1; SMN2AKR1C3CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.