SCHEMBL25813557

SCHEMBL25813557

CC1(C)c2ccccc2-c2cc(-c3cccc(N(c4ccc(-c5ccc6c(c5)oc5ccccc56)cc4)c4ccc5c(c4)C(C)(C)c4ccccc4-5)c3)ccc21

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 1/20 0.34
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
MMP12 P39900 1/20 0.31
MMP13 P45452 1/20 0.31
ALK Q9UM73 1/20 0.31
PRKDC P78527 1/20 0.31
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31
AHR P35869 1/20 0.30
PGR P06401 1/20 0.30
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25814267 0.99 HCRTR1 (0.33) HCRTR1MEN1MAPTKMT2AKDM4E
SCHEMBL25813787 0.98 HCRTR1 (0.33) HCRTR1MEN1MAPTKMT2AKDM4E
SCHEMBL24155982 0.97 HCRTR1 (0.35) HCRTR1MEN1MAPTKMT2AKDM4E
SCHEMBL23376220 0.96 HCRTR1 (0.35) HCRTR1MEN1MAPTKMT2AKDM4E
SCHEMBL25813553 0.96 HCRTR1 (0.35) HCRTR1MEN1MAPTKMT2AKDM4E
SCHEMBL25813554 0.96 HCRTR1 (0.35) HCRTR1MEN1MAPTKMT2AKDM4E
SCHEMBL25813481 0.96 MEN1 (0.35) HCRTR1MEN1MAPTKMT2AKDM4E
SCHEMBL25814185 0.96 MEN1 (0.35) HCRTR1MEN1MAPTKMT2AKDM4E
SCHEMBL20799874 0.95 MMP12 (0.34) HCRTR1MEN1MAPTKMT2AKDM4E
SCHEMBL25813786 0.95 HCRTR1 (0.34) HCRTR1MEN1MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-13 US disclosed
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES SELE, EPHA6, EPX HCRTR1 4519/4885MEN1 1396/4885MAPT 3046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.