SCHEMBL2581397

SCHEMBL2581397

CCCCCCCCCCCCCCCCC(C(=O)OC(C)C)C(C)C

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
FAAH O00519 5/20 0.46
ABCB1 P08183 1/20 0.45
ZDHHC7 Q9NXF8 1/20 0.44
ACE2 Q9BYF1 1/20 0.42
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
GPR84 Q9NQS5 3/20 0.41
CA1 P00915 2/20 0.41
FFAR1 O14842 1/20 0.41
MAPT P10636 1/20 0.40
LCK P06239 1/20 0.40
PPARD Q03181 1/20 0.40
ZDHHC20 Q5W0Z9 1/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26981009 1.00 LMNA (0.52) LMNAFAAHABCB1ZDHHC7ACE2
SCHEMBL442243 1.00 LMNA (0.52) LMNAFAAHABCB1ZDHHC7ACE2
SCHEMBL1032914 1.00 LMNA (0.52) LMNAFAAHABCB1ZDHHC7ACE2
SCHEMBL28525744 1.00 LMNA (0.52) LMNAFAAHABCB1ZDHHC7ACE2
SCHEMBL28477983 1.00 LMNA (0.52) LMNAFAAHABCB1ZDHHC7ACE2
Methylamine SCHEMBL9488577 0.96 LMNA (0.49) LMNAFAAHABCB1ZDHHC7ACE2
SCHEMBL28488646 0.92 LMNA (0.46) LMNAFAAHABCB1ZDHHC7CA1
SCHEMBL19899177 0.91 FAAH (0.44) LMNAFAAHMAPTPPARD
SCHEMBL28404579 0.84 LMNA (0.48) LMNAFAAHZDHHC7CA1
SCHEMBL3179799 0.83 ZDHHC7 (0.46) LMNAFAAHABCB1ZDHHC7ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4731384-A ADJUVANTS, ANTIINFLAMMATORY AGENTS TROPONWERKE GMBH & CO, KG (DE) 1988-03-15 US claimed
CN-114555047-B Water-in-oil type emulsified cosmetic 花王株式会社 2024-12-20 CN disclosed
CN-111088118-B Cleaning composition 日油株式会社 2023-08-01 CN disclosed
US-8048406-B2 Antiperspirant THE DIAL CORPORATION (US) 2011-11-01 US disclosed
EP-1579846-A2 Personal care product THE GILLETTE COMPANY (US) 2005-09-28 EP disclosed
EP-1361852-A2 PERSONAL CARE PRODUCT THE GILLETTE COMPANY (US) 2003-11-19 EP disclosed
WO-2002065998-A2 PERSONAL CARE PRODUCT THE GILLETTE COMPANY (US) 2002-08-29 WO disclosed
EP-0514934-A1 Optically clear hair care compositions containing silicone based microemulsions DOW CORNING CORPORATION (US) 1992-11-25 EP disclosed
US-4731384-A ADJUVANTS, ANTIINFLAMMATORY AGENTS TROPONWERKE GMBH & CO, KG (DE) 1988-03-15 US disclosed