SCHEMBL1032914

SCHEMBL1032914

CCCCCCCCCCCCCCC(C(=O)OC(C)C)C(C)C

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
FAAH O00519 5/20 0.46
ABCB1 P08183 1/20 0.45
ZDHHC7 Q9NXF8 1/20 0.44
ACE2 Q9BYF1 1/20 0.42
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
GPR84 Q9NQS5 3/20 0.41
CA1 P00915 2/20 0.41
FFAR1 O14842 1/20 0.41
MAPT P10636 1/20 0.40
LCK P06239 1/20 0.40
PPARD Q03181 1/20 0.40
ZDHHC20 Q5W0Z9 1/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26981009 1.00 LMNA (0.52) LMNAFAAHABCB1ZDHHC7ACE2
SCHEMBL442243 1.00 LMNA (0.52) LMNAFAAHABCB1ZDHHC7ACE2
SCHEMBL2581397 1.00 LMNA (0.52) LMNAFAAHABCB1ZDHHC7ACE2
SCHEMBL28525744 1.00 LMNA (0.52) LMNAFAAHABCB1ZDHHC7ACE2
SCHEMBL28477983 1.00 LMNA (0.52) LMNAFAAHABCB1ZDHHC7ACE2
Methylamine SCHEMBL9488577 0.96 LMNA (0.49) LMNAFAAHABCB1ZDHHC7ACE2
SCHEMBL28488646 0.92 LMNA (0.46) LMNAFAAHABCB1ZDHHC7CA1
SCHEMBL19899177 0.91 FAAH (0.44) LMNAFAAHMAPTPPARD
SCHEMBL28404579 0.84 LMNA (0.48) LMNAFAAHZDHHC7CA1
SCHEMBL3179799 0.83 ZDHHC7 (0.46) LMNAFAAHABCB1ZDHHC7ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113195060-B External preparation 花王株式会社 2024-04-30 CN disclosed
CN-116685338-A Compositions and methods for improving skin health and for treating and preventing diseases, disorders and conditions associated with fungi and other pathogenic microorganisms 德慕拜昂生物科技公司 2023-09-01 CN disclosed
CN-114401707-A High oil content gel compositions and methods of making and using the same 巴斯夫欧洲公司 2022-04-26 CN disclosed
EP-3808359-A1 COMBINATION OF NATURAL ACTIVE INGREDIENTS PROMOTING APOPTOSIS IN DAMAGED OR SUFFERING SKIN TISSUES Valetudo S.r.l. Con Unico Socio (IT) 2021-04-21 EP disclosed
CN-112351764-A Compositions with increased tonal stability 雅芳产品公司 2021-02-09 CN disclosed
US-20150283048-A1 TEXTILE-SPARING ANTIPERSPIRANT SPRAYS WITH HYDROXYCARBOXYLIC ACIDS HENKEL AG & CO. KGAA (DE) 2015-10-08 US disclosed
US-8409609-B2 Percutaneous absorption-type pharmaceutical preparation NITTO DENKO CORPORATION (JP) 2013-04-02 US disclosed
US-8287846-B2 Cosmetic or dermatological preparations comprising N-acetylcysteine ZAMBON S.P.A. (IT) 2012-10-16 US disclosed
EP-1716850-B1 Transdermal plaster NITTO DENKO CORP (JP) 2012-05-23 EP disclosed
EP-2046277-B1 COSMETIC OR DERMATOLOGICAL PREPARATIONS COMPRISING N-ACETYLCYSTEINE ZAMBON SPA (IT) 2011-01-19 EP disclosed
EP-1731143-A1 Percutaneous absorption-type pharmaceutical preparation using a metal chloride, preferably sodium chloride, for preventing cohesive failure NITTO DENKO CORPORATION (JP) 2006-12-13 EP disclosed
US-20060275354-A1 Percutaneous absorption-type pharmaceutical preparation NITTO DENKO CORPORATION 2006-12-07 US disclosed
EP-1716850-A1 Transdermal plaster NITTO DENKO CORPORATION (JP) 2006-11-02 EP disclosed
US-20060234581-A1 Adhesive preparation NITTO DENKO CORPORATION (JP) 2006-10-19 US disclosed
EP-0891782-B1 Medical adhesive sheet and production thereof NITTO DENKO CORP (JP) 2005-05-25 EP disclosed
US-20040025415-A1 Decorative gel with in situ-formed crystals embedded therein, a process for making the decorative gel and items containing the gel ZIMMERMAN BERNARD (US) 2004-02-12 US disclosed
US-6652606-B1 Decorative gel with in situ-formed crystals embedded therein, candles containing the gel, and a process for making the decorative gel and candles UNGERER & COMPANY 2003-11-25 US disclosed
US-6231883-B1 SHEETS WITH SUPPORTS AND ADHESIVE LAYERS ON SUPPORTS NITTO DENKO CORPORATION (JP) 2001-05-15 US disclosed
EP-0891782-A2 Medical adhesive sheet and production thereof NITTO DENKO CORPORATION (JP) 1999-01-20 EP disclosed
US-4032628-A COSMETIC EMULSION COMPOSITIONS INCLUDING BLACK POLYMER EMULSIFIERS SOCIETE ANONYME DITE: L'OREAL (FR) 1977-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150283048-A1 TEXTILE-SPARING ANTIPERSPIRANT SPRAYS WITH HYDROXYCARBOXYLIC ACIDS HCAR1, HRH1, HRH4 LMNA 3100/4885FAAH 12/4885ABCB1 2188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.