SCHEMBL25814310

SCHEMBL25814310

CC1(C)c2ccccc2-c2cc(-c3cccc(-c4cccc(N(c5cccc(-c6ccccc6)c5)c5cccc(-c6cccc7oc8ccccc8c67)c5)c4)c3)ccc21

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.34
PLA2G4A P47712 3/20 0.34
PLA2G10 O15496 1/20 0.32
ALOX5 P09917 1/20 0.31
CASP3 P42574 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
HCRTR1 O43613 1/20 0.31
ALK Q9UM73 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25813591 0.99 PLA2G2A (0.32) PLA2G2APLA2G4APLA2G10ALOX5CASP3
SCHEMBL25814309 0.98 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10ALOX5ALK
SCHEMBL25814220 0.97 ALK (0.32) PLA2G2APLA2G4AALOX5CASP3SENP7
SCHEMBL25813523 0.97 ALK (0.32) PLA2G2APLA2G4AALOX5CASP3SENP7
SCHEMBL25814221 0.97 ALK (0.32) PLA2G2APLA2G4AALOX5CASP3SENP7
SCHEMBL25813590 0.97 ALK (0.32) PLA2G2APLA2G4AALOX5CASP3SENP7
SCHEMBL25813524 0.97 ALK (0.32) PLA2G2APLA2G4AALOX5CASP3SENP7
SCHEMBL25814237 0.96 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10ALK
SCHEMBL25814236 0.95 PLA2G2A (0.32) PLA2G2APLA2G4APLA2G10CASP3SENP7
SCHEMBL25813820 0.95 PDK2 (0.32) PLA2G2APLA2G4AALOX5CASP3SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-13 US disclosed
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225196-A1 MATERIALS FOR ELECTRONIC DEVICES SELE, EPHA6, EPX PLA2G2A 3035/4885PLA2G4A 4109/4885PLA2G10 4091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.