SCHEMBL25814708

SCHEMBL25814708

CCCc1cc(CCl)ccc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.38
VDR P11473 1/20 0.35
SKP2 Q13309 1/20 0.35
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
ALOX5 P09917 2/20 0.34
FFAR4 Q5NUL3 1/20 0.33
LPL P06858 1/20 0.31
LIPG Q9Y5X9 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
TTR P02766 1/20 0.31
BACE1 P56817 1/20 0.31
MAPT P10636 2/20 0.31
ATM Q13315 1/20 0.31
LMNA P02545 1/20 0.30
XBP1 P17861 1/20 0.30
HIF1A Q16665 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1263571 0.85 CNR1 (0.47) TAAR1VDRSKP2CNR1CNR2
SCHEMBL5598364 0.83 PON1 (0.37) TAAR1CYP3A4TTRHIF1ARAB9A
SCHEMBL4416400 0.80 TAAR1 (0.47) TAAR1VDRSKP2CNR1CNR2
SCHEMBL11366365 0.80 SKP2 (0.56) TAAR1SKP2CNR1CNR2CYP3A4
SCHEMBL11747461 0.78 ALOX5 (0.56) CNR1CNR2ALOX5CYP3A4CYP2D6
SCHEMBL12672918 0.77 TAAR1 (0.36) TAAR1VDRSKP2CNR1CNR2
SCHEMBL9656290 0.75 CNR1 (0.45) TAAR1VDRSKP2CNR1CNR2
SCHEMBL10823208 0.75 CYP3A4 (0.45) TAAR1ALOX5CYP3A4MAPTLMNA
SCHEMBL11869718 0.75 TAAR1 (0.41) TAAR1SKP2CNR1BACE1MAPT
SCHEMBL12642898 0.74 ALDH1A1 (0.51) MAPTLMNAXBP1HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219919-A1 LITHIUM EXTRACTION WITH CROWN ETHERS ORCA HOLDINGS, LLC 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219919-A1 LITHIUM EXTRACTION WITH CROWN ETHERS LCLAT1, LCT, IGF2R TAAR1 1101/4885VDR 302/4885SKP2 4062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.