Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2581477 | 1.00 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL2587436 | 0.85 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL2587432 | 0.85 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL2581029 | 0.81 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL2581025 | 0.81 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL2584841 | 0.81 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL4509622 | 0.81 | — | — | |
| SCHEMBL4509615 | 0.81 | — | — | |
| SCHEMBL2581475 | 0.78 | L3MBTL1 (0.32) | — | |
| SCHEMBL3626367 | 0.78 | L3MBTL1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |