Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2587436 | 1.00 | RIPK1 (0.33) | RIPK1MEN1KMT2A | |
| SCHEMBL2581480 | 0.85 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL2581477 | 0.85 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL4497699 | 0.81 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL4497697 | 0.81 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL2587429 | 0.78 | TDP1 (0.34) | — | |
| SCHEMBL2585730 | 0.75 | FFAR2 (0.34) | RIPK1 | |
| SCHEMBL2585734 | 0.75 | FFAR2 (0.34) | RIPK1 | |
| SCHEMBL2584599 | 0.74 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL2584598 | 0.74 | MEN1 (0.35) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |