Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD1 | P21728 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 4/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14046191 | 0.90 | HRH3 (0.48) | DRD2DRD1HRH3PNMTACACB | |
| SCHEMBL14102479 | 0.90 | HRH3 (0.48) | DRD2DRD1HRH3PNMTACACB | |
| SCHEMBL26227089 | 0.82 | DRD1 (0.47) | DRD2DRD1HRH3DRD4DRD5 | |
| SCHEMBL14027777 | 0.79 | CARM1 (0.45) | DRD2HRH3ACACB | |
| SCHEMBL14027774 | 0.79 | CARM1 (0.45) | DRD2HRH3ACACBHTT | |
| SCHEMBL14046130 | 0.79 | NPSR1 (0.40) | DRD2HRH3KCNH2ACACBHTT | |
| SCHEMBL12628112 | 0.77 | MAOA (0.55) | DRD2DRD1DRD4DRD5SMN1; SMN2 | |
| SCHEMBL7645219 | 0.77 | DRD2 (0.55) | DRD2DRD1HRH3PNMTKCNH2 | |
| SCHEMBL21266992 | 0.76 | ASIC3 (0.44) | DRD2ACACBHTTSMN1; SMN2 | |
| SCHEMBL20883999 | 0.76 | ACACB (0.46) | DRD2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |