Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18052715 | 0.85 | ALDH1A1 (0.48) | SMN1; SMN2PARP1KCNH2MAPTALDH1A1 | |
| SCHEMBL10268271 | 0.84 | MAPT (0.41) | KDM4ESMN1; SMN2PARP1KCNH2MAPT | |
| SCHEMBL27358355 | 0.82 | KDM4E (0.46) | KDM4ESMN1; SMN2DRD2HTR1AADRA1D | |
| SCHEMBL25815331 | 0.82 | MAPT (0.48) | KDM4ESMN1; SMN2DRD2HTR1AADRA1D | |
| SCHEMBL1127846 | 0.81 | MAPT (0.56) | KDM4ESMN1; SMN2DRD2HTR1AADRA1D | |
| SCHEMBL8427926 | 0.80 | ALDH1A1 (0.49) | KDM4ESMN1; SMN2PARP1KCNH2DRD2 | |
| SCHEMBL25815487 | 0.80 | SLC6A2 (0.45) | KDM4ESMN1; SMN2PARP1KCNH2ADRA1D | |
| SCHEMBL8373055 | 0.80 | MAPT (0.56) | SMN1; SMN2MAPTALDH1A1HPGDTSHR | |
| SCHEMBL10264296 | 0.79 | PARP1 (0.42) | SMN1; SMN2PARP1KCNH2MAPTALDH1A1 | |
| SCHEMBL8430119 | 0.79 | ALDH1A1 (0.57) | SMN1; SMN2MAPTALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129506-A1 | POTENT AND SELECTIVE SMARCA2 DEGRADING CHIMERIC MOLECULES AS CANCER THERAPEUTICS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-07-06 | — | — | WO | disclosed |