Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10067362 | 0.83 | MEN1 (0.59) | MEN1KMT2AKIF11NPC1RAB9A | |
| SCHEMBL22330351 | 0.81 | LMNA (0.50) | MEN1KMT2AMAPTHPGDGAA | |
| SCHEMBL10067361 | 0.81 | KMT2A (0.50) | MEN1KMT2AKIF11ALDH1A1KDM4E | |
| SCHEMBL10067389 | 0.81 | LMNA (0.49) | MEN1KMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL15099974 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AKIF11ALDH1A1KDM4E | |
| SCHEMBL10067388 | 0.79 | NPC1 (0.44) | MEN1KMT2AKIF11ALDH1A1KDM4E | |
| SCHEMBL10067359 | 0.79 | KDM4E (0.44) | MEN1KMT2AKIF11ALDH1A1KDM4E | |
| SCHEMBL10067367 | 0.78 | MEN1 (0.43) | MEN1KMT2AKIF11ALDH1A1KDM4E | |
| SCHEMBL10082774 | 0.78 | L3MBTL1 (0.60) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL10067372 | 0.78 | MEN1 (0.43) | MEN1KMT2AKIF11ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3675847-B1 | SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H LUNDBECK AS (DK) | 2023-07-12 | — | — | EP | disclosed |