Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22669310 | 0.83 | KMT2A (0.49) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL20999342 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL25801914 | 0.81 | MRGPRX4 (0.46) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL19569741 | 0.79 | MRGPRX4 (0.46) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL20974037 | 0.79 | ATF4 (0.56) | ALDH1A1HPGDMRGPRX4RAB9ATSHR | |
| SCHEMBL22669451 | 0.78 | KDM4E (0.43) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL19555277 | 0.78 | MRGPRX4 (0.59) | ALDH1A1HPGDKDM4EMRGPRX4GLA | |
| SCHEMBL22669316 | 0.78 | HPGD (0.43) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL20999307 | 0.78 | MRGPRX4 (0.39) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL20999692 | 0.78 | HPGD (0.43) | ALDH1A1HPGDMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452456-B1 | BICYCLIC MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2023-07-05 | — | — | EP | disclosed |