SCHEMBL25817312

SCHEMBL25817312

CC(C)(C)c1nc(C(C)(C)C)c2oc3ccccc3c2n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.49
▸ ALDH1A1 P00352 4/20 0.49
▸ KMT2A Q03164 3/20 0.49
▸ MEN1 O00255 2/20 0.49
▸ GLA P06280 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ LMNA P02545 5/20 0.43
▸ TP53 P04637 2/20 0.43
▸ HTT P42858 1/20 0.43
▸ RXFP1 Q9HBX9 1/20 0.43
▸ MAPT P10636 5/20 0.42
▸ NPSR1 Q6W5P4 2/20 0.42
▸ HPGD P15428 2/20 0.42
▸ TSHR P16473 2/20 0.42
▸ POLB P06746 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ MAPK1 P28482 2/20 0.41
▸ HRH4 Q9H3N8 1/20 0.41
▸ USP2 O75604 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19161213 0.86 LMNA (0.55) KDM4EALDH1A1KMT2AMEN1LMNA
SCHEMBL25016487 0.84 KDM4E (0.47) KDM4EALDH1A1KMT2AMEN1GLA
SCHEMBL19161188 0.84 ALDH1A1 (0.53) KDM4EALDH1A1KMT2AMEN1GLA
SCHEMBL31673315 0.83 SMN1; SMN2 (0.55) KDM4EALDH1A1KMT2AMEN1GLA
SCHEMBL19162676 0.82 MAPT (0.56) KDM4EALDH1A1KMT2AMEN1LMNA
SCHEMBL19161618 0.80 MAPT (0.49) KDM4EALDH1A1KMT2AMEN1GLA
SCHEMBL19161275 0.80 MAPT (0.54) KDM4EALDH1A1KMT2AMEN1LMNA
SCHEMBL19161958 0.79 ALDH1A1 (0.42) KDM4EALDH1A1KMT2AMEN1GLA
SCHEMBL19162671 0.78 MAPT (0.47) KDM4EALDH1A1KMT2AMEN1GLA
SCHEMBL23625959 0.77 SMN1; SMN2 (0.61) KDM4EALDH1A1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230217825-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-07-06 — — US disclosed
US-20230217825-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-07-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230217825-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME OR10J3, AOC2, EPCAM KDM4E 1669/4885ALDH1A1 489/4885KMT2A 1952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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