SCHEMBL25817319

SCHEMBL25817319

CC(C)(C)c1nc2ccc3ccccc3c2nc1C(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 0.45
PRMT3 O60678 1/20 0.45
CARM1 Q86X55 1/20 0.45
EHMT2 Q96KQ7 1/20 0.45
PRMT6 Q96LA8 1/20 0.45
PRMT1 Q99873 1/20 0.45
WDR77 Q9BQA1 1/20 0.45
SLC2A1 P11166 1/20 0.45
MAOA P21397 1/20 0.41
CYP3A4 P08684 2/20 0.40
TDP1 Q9NUW8 2/20 0.39
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP2A6 P11509 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TYMS P04818 2/20 0.39
ALOX5 P09917 1/20 0.38
MAPT P10636 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25877958 0.88 PRMT5 (0.45) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL26051246 0.88 PRMT5 (0.42) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL23473566 0.87 LMNA (0.40) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL23473779 0.87 LMNA (0.40) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL25821952 0.85 PRMT5 (0.40) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL25038073 0.85 NPC1 (0.38) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL23473871 0.85 AKT1 (0.40) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL23473567 0.81 MAOA (0.38) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL23473564 0.81 MAOA (0.38) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL5470832 0.80 PRMT5 (0.56) PRMT5PRMT3CARM1EHMT2PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230217825-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230217825-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME OR10J3, AOC2, EPCAM PRMT5 3100/4885PRMT3 3721/4885CARM1 3222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.