SCHEMBL25817376

SCHEMBL25817376

CC(C)(C)c1nc(-c2cccc3c2sc2ccccc23)nc(C(C)(C)C)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 1/20 0.44
ALOX5 P09917 1/20 0.43
MAPT P10636 1/20 0.40
PRKDC P78527 7/20 0.37
PIK3CD O00329 2/20 0.37
PIK3CB P42338 2/20 0.37
GPR3 P46089 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ATM Q13315 1/20 0.37
TNKS O95271 1/20 0.36
TNKS2 Q9H2K2 1/20 0.36
HTT P42858 1/20 0.34
PAX8 Q06710 1/20 0.34
BRD4 O60885 1/20 0.33
PIK3CA P42336 1/20 0.33
MTOR P42345 1/20 0.33
PIK3CG P48736 1/20 0.33
KCNH2 Q12809 1/20 0.33
BRDT Q58F21 1/20 0.33
HRH4 Q9H3N8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25878028 0.97 PARP14 (0.44) PARP14ALOX5MAPTPRKDCPIK3CD
SCHEMBL19977480 0.91 ALOX5 (0.42) PARP14ALOX5MAPTPRKDCPIK3CD
SCHEMBL25878087 0.87 KDM4E (0.43) PARP14ALOX5MAPTL3MBTL1HTT
SCHEMBL25878024 0.86 ALOX5 (0.44) PARP14ALOX5MAPTPRKDCPIK3CD
SCHEMBL25878094 0.84 AR (0.36) PARP14ALOX5MAPTPRKDCPIK3CD
SCHEMBL10029285 0.84 ALOX5 (0.53) PARP14ALOX5MAPTPRKDCPIK3CD
SCHEMBL25817385 0.82 GPR3 (0.37) PARP14MAPTGPR3L3MBTL1TNKS
SCHEMBL18415772 0.80 PARP14 (0.47) PARP14ALOX5MAPTPRKDCPIK3CD
SCHEMBL20110484 0.80 PARP14 (0.47) PARP14ALOX5MAPTPRKDCPIK3CD
SCHEMBL21304493 0.80 TNKS (0.48) PARP14ALOX5MAPTPRKDCPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230217825-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230217825-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE USING SAME OR10J3, AOC2, EPCAM PARP14 4009/4885ALOX5 693/4885MAPT 1654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.