SCHEMBL2581741

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2578253	0.95	CHRM1 (0.40)	CHRM1MTNR1AMTNR1BKMT2AHDAC1
	SCHEMBL2465064	0.91	HDAC1 (0.38)	CHRM1MTNR1AMTNR1BHDAC1HDAC6
	SCHEMBL2495082	0.89	CHRM1 (0.40)	CHRM1HDAC1HDAC6HTR1AHTR7
	SCHEMBL2578373	0.88	MTNR1A (0.39)	CHRM1MTNR1AMTNR1BKMT2AALDH1A1
	SCHEMBL12160516	0.87	ACHE (0.40)	ACHEKMT2AALDH1A1HTR1AHTR7
	Hydrochloric Acid SCHEMBL2463912	0.87	ACHE (0.39)	ACHEKMT2AALDH1A1HTR1AHTR7
	SCHEMBL2461696	0.86	ACHE (0.42)	ACHEKMT2AHTR1AHTR7
	SCHEMBL2495645	0.86	CHRM1 (0.41)	CHRM1ALDH1A1HTR1AHTR7
	SCHEMBL2463173	0.85	CHRM1 (0.42)	CHRM1KMT2AHDAC1HDAC6ALDH1A1
	SCHEMBL2489835	0.85	CHRM1 (0.38)	CHRM1HDAC1HDAC6HTR1AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.