Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 3/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 7/20 | 0.45 |
| ▸ | DRD4 | P21917 | 6/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31587053 | 0.88 | HTR1A (0.48) | DDB1CRBNHTR1AHTR7DRD2 | |
| SCHEMBL31586422 | 0.88 | HTR1A (0.48) | DDB1CRBNHTR1AHTR7DRD2 | |
| SCHEMBL31586109 | 0.86 | DDB1 (0.50) | DDB1CRBNHTR1AHTR7DRD2 | |
| SCHEMBL7270516 | 0.77 | HTR1A (0.72) | HTR1AHTR7PAOXDRD2DRD4 | |
| SCHEMBL29680752 | 0.77 | DRD2 (0.55) | DDB1CRBNDRD2DRD4 | |
| SCHEMBL30678689 | 0.77 | DDB1 (0.56) | DDB1CRBN | |
| SCHEMBL25035204 | 0.76 | HTR7 (0.50) | DDB1CRBNHTR1AHTR7 | |
| SCHEMBL31355842 | 0.74 | CA1 (0.57) | DDB1CRBNCACNA1G | |
| SCHEMBL22941401 | 0.74 | DDB1 (0.43) | DDB1CRBNHTR1AHTR7 | |
| SCHEMBL31485110 | 0.73 | CHRNA7 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116934-A1 | KRASG12D PROTEIN HYDROLYSIS REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |