Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.31 |
| ▸ | NPC1 | O15118 | 4/20 | 0.31 |
| ▸ | RAB9A | P51151 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.30 |
| ▸ | TP53 | P04637 | 3/20 | 0.30 |
| ▸ | CASP1 | P29466 | 3/20 | 0.30 |
| ▸ | CASP7 | P55210 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14341761 | 0.74 | ALDH1A1 (0.49) | PDE10AALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL13804550 | 0.71 | PTGS2 (0.39) | PTGS2SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL23047161 | 0.68 | PDE10A (0.44) | PDE10APTGS2ALDH1A1HSD17B10HPGD | |
| SCHEMBL16646633 | 0.68 | MAPT (0.44) | PDE10APTGS2ALDH1A1HSD17B10HPGD | |
| SCHEMBL15061959 | 0.67 | PTGS2 (0.32) | PDE10APTGS2 | |
| SCHEMBL24716552 | 0.67 | PDE10A (0.30) | PDE10A | |
| SCHEMBL3833766 | 0.65 | ALDH1A1 (0.38) | ALDH1A1HSD17B10HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7452681 | 0.65 | SMPD3 (0.49) | ALDH1A1NPC1MAPTL3MBTL1MAPK1 | |
| SCHEMBL31717021 | 0.65 | SMN1; SMN2 (0.43) | ALDH1A1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL25818110 | 0.65 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133575-A2 | DYEING COMPOSITION COMPRISING A SECONDARY PARA-PHENYLENEDIAMINE OXIDATION BASE AND A SILICONE FATTY SUBSTANCE OR A NON-SILICONE LIQUID FATTY SUBSTANCE | L'OREAL (FR) | 2010-11-25 | — | — | WO | disclosed |