Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25818121 | 0.90 | BCHE (0.43) | MTNR1AMTNR1BBCHEPPARGPPARA | |
| SCHEMBL13881804 | 0.88 | CHRM2 (0.50) | MTNR1AMTNR1BBCHEPPARGPPARA | |
| SCHEMBL2204946 | 0.85 | TAAR1 (0.47) | BCHEPPARGPPARACYP2D6CHRM2 | |
| SCHEMBL4568762 | 0.84 | PPARA (0.52) | BCHEPPARGPPARACYP2D6ALDH1A1 | |
| SCHEMBL25820080 | 0.81 | CYP2D6 (0.56) | PPARGPPARACYP2D6KDM4EALDH1A1 | |
| SCHEMBL25822184 | 0.80 | MAPK1 (0.46) | MTNR1AMTNR1BCYP2D6KDM4EALDH1A1 | |
| SCHEMBL13881576 | 0.79 | BCHE (0.42) | MTNR1AMTNR1BBCHEPPARGPPARA | |
| SCHEMBL20318730 | 0.78 | PPARA (0.49) | BCHEPPARGPPARACYP2D6ALDH1A1 | |
| SCHEMBL25821806 | 0.78 | KDM4E (0.56) | MTNR1AMTNR1BBCHECYP2D6CHRM2 | |
| SCHEMBL13881720 | 0.77 | CHRM2 (0.48) | MTNR1AMTNR1BBCHEPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | MTNR1A 93/4885MTNR1B 92/4885BCHE 1649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.